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May 3, 1941


JAMA. 1941;116(18):2014-2015. doi:10.1001/jama.1941.62820180002006a

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The following case is presented because of its significance to wartime medicine. Tetanus is comparatively rare in civil life, and there has been little opportunity to observe the effect of the new sulfonamide preparations in this disease. In the case here reported 110,000 units of tetanus antitoxin was given for the original attack, with recurrence eighteen days later. The second attack was successfully treated with azosulfamide.


History.—  A youth aged 19, a mill worker, seen with Dr. E. M. Chew in consultation, was admitted to the Ballard General Hospital July 29, 1940 with headache, nausea, vomiting, numbness of the hands and chin, abdominal pain, inability to void, mild delirium and tetanic convulsions. The mode of infection was uncertain. A week before he had chafed his thighs while riding a horse and two or three weeks before had bruised a toe and injured a finger while working.

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