The ventricular rate serves as the chief guide to the degree of digitalization of patients with auricular fibrillation. The customary procedure is to give enough digitalis to reduce the rate of the ventricles to about 70 beats a minute and to maintain it at that level. It is well known, however, that if this result is attained with the patient at complete physical rest the rate in some cases mounts considerably when the patient is up and about. Furthermore, it may show wide fluctuations with moderate effort. Sir Thomas Lewis1 stated: "Although it is usually possible to control the rate in cases of auricular fibrillation, when the patients are at rest or quietly exercising, it is rarely possible to control the rates adequately in conditions of freer exercise." In a recent report by Weinstein, Plaut and Katz2 a contrary observation was made. In a previous study3 it
MODELL W, GOLD H, ROTHENDLER HH. USE OF DIGITALIS TO PREVENT EXAGGERATED ACCELERATION OF THE HEART: DURING PHYSICAL EXERCISE IN PATIENTS WITH AURICULAR FIBRILLATION. JAMA. 1941;116(20):2241–2244. doi:10.1001/jama.1941.02820200011003
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: