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A widow, aged 33, who had two children living and well, the youngest aged 2, and who had aborted the second month, in 1924, developed varicose veins in both legs during her first pregnancy. Rupture of the veins had not occurred. The Wassermann reaction was negative. The patient was treated by elastic stockings with complete relief until June 3, 1927, when she went to the university dispensary and received injections for varicose veins, with salt solution and calorose, June 3 and again June 8. She felt perfectly well until June 13, when at 5 p. m., while playing with her children, she fell dead.
Autopsy revealed a well developed, well nourished white woman, 165 cm. in length and weighing about 140 pounds (63.5 Kg.). Rigor was present in the legs. There was purplish hypostasis; there was no edema, cyanosis or jaundice. The pupils were equal and regular. Varicose veins
Olson OA. FATALITY FOLLOWING VARICOSE VEIN INJECTION. JAMA. 1927;89(9):692. doi:10.1001/jama.1927.92690090002012a
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