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September 3, 1927


JAMA. 1927;89(10):794. doi:10.1001/jama.1927.02690100056017

It has been only a few years since the alphabet was requisitioned, so to speak, for the specific designation of a series of food factors as yet chemically undefined but nevertheless clearly essential to physiologic well being. Although vitamins A, B, C, D and E have thus found their way into the scientific literature of the present day, it is by no means certain, if indeed it is even probable, that the list of these heretofore unidentified dietary constituents which insure proper nutrition has been exhausted. While the existence and importance of some of the designated vitamins have now been generally accepted, others have remained the subject of considerable debate. Thus, opinion has been divided as to whether there is any vitamin, such as E is alleged to be, that is specific for the reproductive functions. Several investigators have contended that, if the diet is adequately supplied with all the