Since the introduction by Sicard and Forestier1 of iodized oil as an aid in roentgen-ray diagnosis, it has been very widely used in connection with the roentgen ray, not only in the spinal canal but also in various other organs and structures of the body as a diagnostic procedure.
The French preparation lipiodol, and the Danish preparation iodumbrin, are said to be very closely similar in that they contain approximately equal amounts of iodine (40 per cent), and in that they are both highly stable. The relative stability of these compounds is evidenced by the few reports of untoward symptoms following their use during the five years of their employment.
Here and there one finds fever and dyspnea reported immediately after the use of these oils. O. Lichtwitz2 reported a rapidly progressive pulmonary tuberculosis which flared up after their use, and Moeller and von Magnus3 and Armand-DeLille
BELOTE GH. IODODERMA FROM IODIZED OIL. JAMA. 1927;89(11):882. doi:10.1001/jama.1927.02690110046016
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