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Article
July 26, 1941

GONOCOCCIC CONJUNCTIVITIS: A COMPARISON OF SULFANILAMIDE, SULFAPYRIDINE AND SULFATHIAZOLE IN THE TREATMENT OF ONE HUNDRED AND TWENTY CASES

Author Affiliations

MEMPHIS, TENN.
From the Department of Ophthalmology of the University of Tennessee College of Medicine.

JAMA. 1941;117(4):250-252. doi:10.1001/jama.1941.02820300014004
Abstract

In the past few years so many articles have appeared in the ophthalmic journals concerning the treatment of gonococcic conjunctivitis with sulfanilamide that one hesitates to burden the literature with any further reports. However, considerable difference of opinion still exists as to the best method of using the drug. While most observers have used the sulfonamides orally, several have reported their experiences with the drugs used locally in the eye. Rein and Tibbetts1 employed a 0.5 per cent solution of sulfanilamide in physiologic solution of sodium chloride as an irrigation every fifteen minutes night and day. They reported good results in 15 cases, in which negative smears were obtained on an average of six and eight-tenths days. Panneton2 has recently published an interesting account of treating this disease in 10 cases by the insufflation of the conjunctival sac with the powdered drug every three hours. In 8 he

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