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Article
August 2, 1941

THE TREATMENT OF PARKINSONISM: RESULTS OBTAINED WITH WINE OF BULGARIAN BELLADONNA AND THE ALKALOIDS OF THE U. S. P. BELLADONNA

Author Affiliations

BOSTON
From the Neurological Unit, Boston City Hospital, and the Department of Neurology, Harvard Medical School.

JAMA. 1941;117(5):335-337. doi:10.1001/jama.1941.02820310007004
Abstract

Ivan Raeff, of Chipka, Bulgaria, a biologist, in 1926 made a decoction of the root of the Bulgarian belladonna plant with wine and instituted an elaborate procedure for the treatment of parkinsonism. Most astonishing results were claimed. Since Raeff's study there have been many reports in the literature on the use of Bulgarian belladonna.1 Elaborate side measures which were part of the therapeutic program of some investigators included change in environment, special nursing care, physical therapy, systematic exercises and occupational therapy. In addition, the psychologic effect of the sympathy and attention given the patients must have been considerable.

It has been stated that in the treatment of patients with parkinsonism Bulgarian belladonna has a value superior to that of the belladonna grown in other countries. This claim has not been supported by the results of investigators using the English, Italian or German root. It was the purpose of our

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