Primary sarcoma of the gallbladder is rare. Kaufmann1 states that there are only thirteen cases on record. Landsteiner,2 in 1904, was the first to summarize the literature on the subject and to that date was able to collect only six alleged cases. Three of these, he stated, could not be definitely considered primary sarcomas of the gallbladder and in the other three the diagnosis was not finally accepted by him because the original descriptions were not available. Landsteiner's own case was a myosarcoma. At a later date he described another gallbladder exhibiting a spindle cell sarcoma and a squamous cell carcinoma.3 Bayer4 reported a case of myxochondro-osteosarcoma with adenomatous hyperplasia of Luschka's ducts. Parlavecchio,5 Hotes,6 Bayer,4 Griffon and Segal,7 Iwasaki,8 and Jaffé9 have each recorded a case of spindle cell sarcoma of the gallbladder; in some of these, giant cells
Brunschwig A. PRIMARY SARCOMA OF THE GALLBLADDER. JAMA. 1931;96(9):680–681. doi:10.1001/jama.1931.27220350001010
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