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August 2, 1941

Clinical Pellagra

JAMA. 1941;117(5):404. doi:10.1001/jama.1941.02820310076032

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The book is divided into an introductory chapter and seven sections dealing successively with history and epidemiology, the quest for the cause of pellagra, etiology and pathology, clinical investigations, symptomatology, diagnosis and prognosis, prophylaxis and treatment. These sections and chapters present a mixture of the good and the poor. For example, nowhere else can the student of pellagra find as complete a history of the disease, such a detailed yet clear description of the clinical pictures (well illustrated by photographs) found in pellagrins or the excellent summaries of recent clinical investigations into pellagra as conducted at Duke University and the University of Georgia. On the other hand, the chapter on the genesis of pellagra appears to have been written by one who resents the intrusion of nicotinic acid and other vitamins into a long held theory based on hypothetic toxins present in corn and alcohol. He states that "thus nicotinic

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