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September 17, 1927

Les cancers et leurs complications. Étude clinique de leur évolution. Par Maurice Renaud, médecin des Hôpitaux de Paris.

JAMA. 1927;89(12):989. doi:10.1001/jama.1927.02690120065038

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This is a timely aid for physicians in general practice. It deals with such local complications of malignant tumors as hemorrhage, ulceration and pressure which practitioners are disposed to consider. The main portion is devoted, however, to matters more commonly not thought of at all, or improperly disregarded. These are the systemic effects on metabolism, the results of infection, of tissue destruction and fever, and the influence malignant tumors have on the reaction to incidental infections, such as erysipelas. The anemia accompanying cancer is reviewed, also the particular disease elements composing the vague state known so long as cachexia. The disturbances of function of single organs or sets of organs, regardless of whether they are or are not the seat of primary or secondary tumors, are also presented concisely. For example, it is important to learn that a thrombo-ulcerative endocarditis was found in fourteen of 136 bodies examined, all bodies

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