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August 16, 1941

O prodolzhitelnosti zhizni geterogennykh i gomogennykh eritrotsitov v krovyanom rusle rettsipienta; eksperimentalnoe issledovanie

JAMA. 1941;117(7):574. doi:10.1001/jama.1941.02820330078030

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The monograph deals with an experimental attempt to determine the survival of the transfused red blood cells in the circulation of the recipient. Experiments were made with both heterogenous and homogenous bloods. The method of investigation developed by the author is based on the well known phenomenon of Bordet that serum of an animal of a certain species when immunized with erythrocytes of an animal of another species acquires the property of dissolving erythrocytes of the latter only. The method allows of both the qualitative and the quantitative determination of the erythrocytes in the blood circulation of the recipient. Transfused heteroerythrocytes are eliminated rapidly, although wide differences were found for different species. Homoerythrocytes of the citrated blood, on the other hand, survive up to two months. The erythrocytes of conserved blood are eliminated from the circulatory blood of the recipient as early as the fifth day. This is a worth

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