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September 24, 1927

The Inflammatory and Toxic Diseases of Bone: A Text-Book for Senior Students.

JAMA. 1927;89(13):1082. doi:10.1001/jama.1927.02690130070038

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As this is a textbook for senior students, the matter is presented concisely. The author realizes that it is not easy to draw the line between the inflammatory and the toxic diseases. In both, toxins and inflammatory changes are associated; but a distinction may be made between toxins produced locally by micro-organisms and circulating toxins derived from a distant source, not necessarily of micro-organic origin. The author has included a discussion of osteogenesis imperfecta, which formed the subject of a Hunterian lecture and is therefore included in this book although he realizes it is neither an inflammatory nor a toxic disease, but a disorder of growth. Two other subjects—osteitis fibrosa and osteitis deformans—were dealt with in Hunterian lectures, and all three were published in the British Journal of Surgery, as well as the chapters on spondylitis deformans and leontiasis ossea. The subject matter is presented from the clinical point of

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