The choice of treatment for cancer of the lower lip varies widely in the different medical centers where large numbers of patients with this condition are seen. Physicians who attempted the use of radium and roentgen rays with inadequate doses in the early periods of these forms of therapy immediately turned to more satisfactory means of treating malignant lesions by actual cauterization and plastic surgical operations. These methods have been carefully developed, and their application is successful in producing cures.1 Equally successful has been the use of irradiation by roentgen rays and radium when employed in sufficient doses.2
In our hands, the most successful treatment for cancer of the lip has been a combination of the gamma rays of radium with unfiltered or lightly filtered roentgen rays. This will provide an adequate dose by treatment on successive days to effect a total, continuous or massive dose, which is
LAMB JH, EASTLAND WE. CANCER OF THE LOWER LIP: TREATMENT WITH RADIATION. JAMA. 1941;117(8):600–607. doi:10.1001/jama.1941.02820340022007
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