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August 30, 1941


JAMA. 1941;117(9):789-790. doi:10.1001/jama.1941.02820350129012

The common cause of coronary occlusion is thrombosis secondary to sclerosis of the coronary vessels. Embolism of the coronary arteries is rare. The first case of this type was described by Virchow in 1856. Saphir,1 in an exhaustive review of the literature, collected 11 cases, to which he added 3 observations of his own. Garvin and Work2 have encountered 3 cases of coronary embolism among 12,300 consecutive necropsies. Levy, Bruenn and Kurtz found 6 instances of embolism in a study of the records of 762 cases of coronary occlusion, Appelbaum and Nicolson 4 cases among 168, Kirschbaum 4 among 612 cases of severe disease of the coronary arteries. Coronary embolism, according to Hamman,3 was registered at the Johns Hopkins Hospital for the first time in a period of more than fifty years in 1931, and then ten times in the succeeding nine years. Hamman believes that the