One of the characteristics of modern medicine is the success with which sciences not primarily biologic have been employed in the expansion of the knowledge of disease and in the increase in facility and accuracy of diagnosis. Both chemistry and physics play an important part in current medical thought and practice. Internal medicine, especially, has appropriated the device of blood analysis and has profited immensely by so doing. The rationale of the use of such analytic chemical data is based on the conception of the blood as the primary transporting system of the body, carrying not only nutrients to the cells but, what is more significant from the diagnostic point of view, removing waste products from the site of formation to the excretory organs. An abnormal concentration of metabolites can thus be attributed to excessive production or to defective elimination. In general, the determination for the constituent in question has
UNLAKED BLOOD FOR CHEMICAL ANALYSIS. JAMA. 1931;96(10):776–777. doi:10.1001/jama.1931.02720360046014
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