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Article
October 11, 1941

BROMIDE INTOXICATION OF UNUSUAL SEVERITY AND CHRONICITY RESULTING FROM SELF MEDICATION WITH BROMO-SELTZER

Author Affiliations

Chicago; Cincinnati; Chicago
From the Division of Neurosurgery of the University of Chicago Clinics.

JAMA. 1941;117(15):1256-1258. doi:10.1001/jama.1941.72820410001010
Abstract

Numerous reports1 have called attention to the fact that severe psychosis, with mental deterioration, loss of memory, delirium and hallucinosis, is not uncommon as a result of intoxication with bromides. Moore, Sohler and Alexander,2 in a review of the recent literature have pointed out that "the duration of bromide intoxication from the appearance of the first symptoms to the disappearance of the major toxic signs" is usually a matter of only two to eight weeks. In the present instance a progressive mental deterioration which was present for eleven to fifteen years and culminated in a state of complete mental confusion, amnesia, disorientation and hallucinosis resulted from continuous self medication with large quantities of bromo-seltzer. Recently in The Journal3 attention has been called to the dangers of intoxication with bromides and the dangers arising from self medication with certain proprietary preparations containing bromide salts. Other instances of intoxication

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