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October 29, 1927


JAMA. 1927;89(18):1518-1519. doi:10.1001/jama.1927.02690180050016

When three babies are born to three different Smith families in the same hospital at about the same time and the mother of one claims she has been given the wrong child, can a study of the blood grouping in each family aid in establishing the relationship? The answer is, It may. The designation of the four blood groups as O, A, B and AB (corresponding to Jansky's groups 1, 2, 3 and 4) indicates directly the presence of the agglutinogens A and B, the agglutinable substances of the corpuscles. The inheritance of these blood groups, which is in accordance with the mendelian laws, depends chiefly on the factors A and B which are dominant to the factor O determining the absence of agglutinogens. The inheritance is not sex-linked and its application to problems of parental relationship is based on a single fact: an agglutinogen (A or B) that is