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October 11, 1941

Malignant Disease and Its Treatment by Radium

JAMA. 1941;117(15):1304. doi:10.1001/jama.1941.02820410082041

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This large volume represents the personal experience and point of view of the author, long an English leader in radium therapy. The technic and end results are based on an experience in the radiation treatment of more than three thousand cancers during the period of 1924 to 1939.

There are three major subdivisions of the book. The first section, dealing with the physics of radiation, includes chapters on radioactivity, radium dosimetry, general principles of technic in radium therapy and teleradium treatment. The second section is devoted to the biologic effects of radiation, such as radiosensitivity, the mode of action of radiation, the effects of radium on normal tissues, the effects of radium on malignant tumors and radium dangers and protection. The final section surveys the natural history and treatment of malignant tumors, with the chapters divided according to the region or tissues involved, such as the lip, tongue or breast.

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