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Article
October 18, 1941

SARCOIDOSIS, OR BESNIER-BOECK-SCHAUMANN DISEASE: THE FRANK BILLINGS LECTURE

Author Affiliations

BALTIMORE
From the Medical Clinic, Johns Hopkins University School of Medicine and the Johns Hopkins Hospital.

JAMA. 1941;117(16):1321-1327. doi:10.1001/jama.1941.02820420013005
Abstract

Only within comparatively recent years has the important observation made by Schaumann1 in 1914 been fully appreciated. He showed then that the lesions of the nose, the ears and the fingers described in 1889 by Besnier2 as lupus pernio and the disease affecting the skin, the mucous membranes and the lymph nodes which Boeck3 in 1899 termed sarcoid are the same. He pointed out further that the tonsils, the lungs, the bones and the internal organs are involved in the process and concluded, therefore, that the disease is or may become a generalized one. He found the pathologic lesion to be the same in all organs, and since it involved lymphoid tissue he termed the disease lymphogranuloma benignum to distinguish it from Hodgkin's disease, or lymphogranuloma malignum. Since Schaumann's time the disease has been redescribed under a number of names. Kuznitsky and Bittorf4 in 1915 directed

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