Innumerable vegetable substances, often in the form of powders or teas made from green plants, have been used as popular remedies for diabetes throughout the world. As one example, eucalyptus leaf tea attracted so much notice in some regions that it was investigated at the Physiatric Institute at the special request of the National Research Council, with negative results.1 In 1925, Professor Durig of the University of Vienna became impressed with the benefits of blueberry leaf tea as used for diabetes among the Alpine peasantry2 to such an extent that he suggested an investigation of the question by Dr. Richard I. Wagner, a chemist in his laboratory. Brief summaries of the results of physiologic experiments were published by Dr. Wagner in collaboration with Mark,3 and of clinical observations in collaboration with Mark and Eppinger.4 The blueberry leaf tea showed distinct but variable influence on the alimentary
ALLEN FM. BLUEBERRY LEAF EXTRACT: PHYSIOLOGIC AND CLINICAL PROPERTIES IN RELATION TO CARBOHYDRATE METABOLISM. JAMA. 1927;89(19):1577–1581. doi:10.1001/jama.1927.02690190015005
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