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October 25, 1941


JAMA. 1941;117(17):1447-1448. doi:10.1001/jama.1941.02820430043014

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At a conference on therapy of rheumatoid arthritis held by the members of the Departments of Pharmacology and Medicine of Cornell University Medical College and the New York Hospital, Dr. Harry Gold presented a list of some thirty therapeutic measures. Dr. Russell L. Cecil defined rheumatoid arthritis as a chronic disease of the joints characterized in the early stages by pain and swelling of multiple joints and in the latter stages by ankylosis and deformity. Dr. Cecil stated that the theory of focal infection is generally discredited because in many patients the disease develops without any association with foci, and because patients who have had foci of infection removed have obtained only temporary relief, if any. Bee venom, foreign protein therapy, sulfur, iodides, salicylates and many other drugs have all had their vogue and have all been found more or less ineffective. Dr. Cecil emphasized four principles on which to

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