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November 8, 1941

Das Vitamin K und seine klinische Bedeutung

JAMA. 1941;117(19):1657-1658. doi:10.1001/jama.1941.02820450081033

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The author, a Swiss, is associate professor of internal medicine at the University of Zurich. He has worked in the field of clinical vitamin K investigation since the role of vitamin K in cholemic bleeding tendency became known, and he was the first to describe vitamin K deficiency in adult patients with sprue. Koller's book gives an excellent description of all clinical aspects of vitamin K and also a good explanation of its biology and chemistry. The main object is the critical examination of all the problems which develop in the clinical and pathologic fields more than a detailed account of its recent history. To this purpose the author applies his own clinical material. Methods and means are described in an unusually clear way. One will scarcely find a more efficient account of the use and interpretation of Quick's prothrombin time method than that given by Koller. The vitamin K

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