[Skip to Navigation]
JAMA Clinical Guidelines Synopsis
May 10, 2016

Tobacco Smoking Cessation in Adults and Pregnant Women: Behavioral and Pharmacotherapy Interventions

Author Affiliations
  • 1Section of General Internal Medicine, University of Chicago, Chicago, Illinois
JAMA. 2016;315(18):2011-2012. doi:10.1001/jama.2016.2535

Tobacco use is the leading preventable cause of morbidity and mortality in the United States.1 Smoking is implicated in the development of numerous cancers, respiratory and cardiovascular diseases, diabetes, impaired immune function, macular degeneration, osteoporosis, and infertility and is responsible for 480 000 US deaths each year.1 In pregnant women, smoking increases the risk of congenital malformations, perinatal complications, miscarriages, and stillbirths and leads to poorer neonatal and infant outcomes.1