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Article
November 26, 1927

AN INEFFECTUAL ATTEMPT TO CULTIVATE THE GLOVER ORGANISM FROM CARCINOMAS

Author Affiliations

PHILADELPHIA
From the Research Institute for Cutaneous Medicine, Philadelphia.

JAMA. 1927;89(22):1868-1869. doi:10.1001/jama.1927.02690220044012
Abstract

Of the large number of organisms alleged from time to time by various investigators to be the cause of malignant new growths, that described by Glover has attracted considerable attention.

Up until a year ago, the method employed was not known; but following its publication by Glover,1 we believed it advisable to repeat the work with scrupulous attention to every technical detail.

Our plan also included animal inoculation tests had we succeeded in securing the organism; but cultures of thirteen different tumors, listed in the accompanying table, failed to yield the organism described by him.

Glover described this organism as a gram positive, filtrable, motile organism, and stated that he isolated it and obtained cultures of it from every type of malignant tumor investigated, including human carcinoma, mouse carcinoma (63), rat carcinoma, human sarcoma, rat sarcoma (Jensen) and Rous fowl sarcoma (number 1). It is also stated that the blood

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