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March 28, 1931

Clinical and Epidemiological Observations on Tropical Typhus in the Federated Malay States.

JAMA. 1931;96(13):1100. doi:10.1001/jama.1931.02720390110026

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Experimental Tropical Typhus in Laboratory Animals. By Raymond Lewthwaite. Bulletins from the Institute for Medical Research, Federated Malay States, No. 3 of 1930. Paper. Pp. 10. Kuala Lumpur: Federated Malay States Government Printing Office, 1930.

This is a study of 164 cases of tropical typhus (so called by Fletcher and Lesslar: Bull. Inst. M. Research, Kuala Lumpur, F. M. S., 1925, number 2) occurring in the Federated Malay States from January, 1927, to April, 1929. Of this series 154 were of the K type (rural) and 10 of the W type (urban). Clinically the two types are identical and resemble exanthematic typhus. The clinical and serologic manifestations are given which make possible a differentiation from tsutsugamushi disease, leptospirosis and typhoid. The serum of the urban type agglutinates indologenic strains of Proteus X 19 but not the anindologenic strains. Serum of the rural type agglutinates the anindologenic but not the indologenic

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