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December 20, 1941


Author Affiliations

From the Section on Orthopedic Surgery (Drs. Black and Ghormley) and the Section on Roentgenology (Dr. Camp) of the Mayo Clinic.

JAMA. 1941;117(25):2144-2150. doi:10.1001/jama.1941.02820510032008

The syndrome of senile osteoporosis as it is understood today is different in some respects from its early description. In the early cases the diagnosis was made on the basis of the clinical findings and was confirmed at necropsy; as a consequence the diagnosis was usually made in the advanced stages and the postmortem examination showed extensive osteoporosis. Today, with improved methods for diagnosis, routine roentgenologic examination may disclose the condition even without clinical signs and symptoms.

Our report is based on a study of 208 patients, 167 women and 41 men. The average age of all when first seen at the Mayo Clinic was 62, the youngest being 45 and the oldest 87. In the cases reported in the literature, somewhat more advanced ages were represented. In 42 selected from various reports the mean age was 66. These figures indicate that senile osteoporosis is definitely associated with the older