[Skip to Content]
[Skip to Content Landing]
September 1, 1934


JAMA. 1934;103(9):683-684. doi:10.1001/jama.1934.02750350047017

About a year ago Gershenfeld,1 of the Philadelphia College of Pharmacy and Science, called attention to the fact that solutions marketed in ampules, generally considered to be sterile, may occasionally be contaminated with pathogenic organisms. He reported two cases of suppuration that developed in patients following the injection of the contents of ampules, both from the same batch, although in each case the usual aseptic precautions were taken by the physician. Two ampules from this batch were then examined and each revealed the presence, in pure culture, of Staphylococcus aureus. From a brief survey then made by Gershenfeld, it appeared that many firms fail to indicate on the labels of ampule preparations whether or not these are sterile. The physician ordinarily makes the tacit assumption, when he administers to a patient the contents of a sealed container of this type, that adequate precautions have been taken by the manufacturer to

First Page Preview View Large
First page PDF preview
First page PDF preview