To the Editor Dr Seymour and colleagues1 assessed the predictive validity of various clinical criteria to identify patients with sepsis. However, their conclusion that the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) and quick SOFA (qSOFA) scores are more clinically useful than the systemic inflammatory response syndrome (SIRS) criteria was primarily based on differences in the area under the receiver operating curve (AUROC), which has several limitations.2
Makam AN, Nguyen OK. Clinical Criteria to Identify Patients With Sepsis. JAMA. 2016;316(4):453. doi:10.1001/jama.2016.6407
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: