Methods of treatment of disease, like styles and fabrics of dress, change from year to year and from decade to decade, and in both even a brief historical review will demonstrate a continued repetition of older practices somewhat modified to meet new conditions and modes. In matters of dress, which vary from long to short and back again, the original object of clothing to protect the body from cold and injury seems at times to be lost sight of, and in medicine newly observed or striking effects lead to the revival or popularization of remedies without due regard to ultimate results, on the assumption that these effects are necessarily beneficial to the patient. The occurrence of the changes is evident; their value to the patient requires careful consideration. The ease of use of the hypodermic needle which makes possible the parenteral introduction of proteins into the body has led to
IRONS EE. FACTS AND FALLACIES CONCERNING FOREIGN PROTEIN AND VACCINE THERAPY. JAMA. 1931;96(16):1289–1293. doi:10.1001/jama.1931.02720420013005
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