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April 18, 1931


JAMA. 1931;96(16):1331. doi:10.1001/jama.1931.02720420055028

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To the Editor:  —In The Journal, March 14, a series of articles concerning the uses of narcotics was begun. Your introduction, as usual, is of a high order, showing the object of the essays. On page 858 the following statements are made by Cutler and Holloway: "Unfortunately, science has not yet provided a substitute that will satisfactorily produce anesthesia when placed on the conjunctiva and mucous membrane, although in the former case holocaine is quite useful. Until such a drug is forthcoming, ophthalmologists and otorhinolaryngologists must continue to use cocaine for producing anesthesia by application to surfaces."Such a conclusion is erroneous and does not give the scientific facts. All up-to-date medical men know of the value of p-aminobenzoyl-γ-dinormalbutylaminopropanol sulphate (Butyn) for anesthesia. I hold no brief for Abbott Laboratories, but such a dogmatic statement should not go unchallenged. Also, there is Nupercaine. Why not give these drugs the

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