[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 764
Citations 0
Global Health
August 16, 2016

More Insights Into Zika Virus Infection and Birth Outcomes

Author Affiliations

Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2016;316(7):702. doi:10.1001/jama.2016.10895

Physicians are finding a wider range of congenital abnormalities beyond microcephaly that appear to be associated with Zika virus infection in utero, observations that suggest the presence of a new congenital syndrome, according to a report from the World Health Organization (Costello A et al. Bull World Health Org. 2016;94[6]:406-406A). Zika-related abnormalities include craniofacial disproportion, spasticity, seizures, eye problems, irritability, brainstem dysfunction, and neurological problems that range in severity are being observed in infants born with normal head circumference. Zika infection may also cause problems in cardiac, digestive, and genitourinary systems in infants. Antenatal and postnatal histories as well as follow-up data, laboratory findings, and neuroimaging results will be used to define the new syndrome.