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Comment & Response
September 13, 2016

Sodium Excretion, Cardiovascular Disease, and Chronic Kidney Disease

Author Affiliations
  • 1Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana
JAMA. 2016;316(10):1112-1113. doi:10.1001/jama.2016.11558

In Reply In response to Dr Hursitoglu, we found that the urinary sodium to potassium excretion ratio was not significantly associated with CVD in our study (P for trend = .11). This is likely due to the lack of an inverse association between urinary potassium and CVD among patients with CKD. We additionally adjusted for urinary potassium excretion in a multivariable model and the results were not significantly changed (Table).