The 2010 passage of the Affordable Care Act (ACA) raised numerous opportunities for disease prevention. Of the 10 legislative titles comprising the ACA legal framework, Title 4 (“Prevention of Chronic Disease and Improving Public Health”) initially held the most promise for delivering new financial resources as well as effective policy for prevention.1 Six years later, Title 4 outcomes show mixed results. In the meantime, however, other ACA innovations are redesigning health systems by incorporating prevention into a range of new care models. Doing so connects the clinic and the community in ways not necessarily envisioned in the statute, thereby broadening possibilities for the future of population health.