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In laryngeal diseases every obtainable aid is necessary in order to make a correct differential diagnosis, for in disease of the larynx early correct diagnosis may mean saving the patient's larynx, and, in many instances, his life as well. Mirror examination alone will seldom give sufficient information for a correct opinion. A routine study should include a careful history, a complete general examination by a competent internist, and serologic studies to exclude syphilis. Roentgen examination of the chest and sputum examinations to exclude tuberculosis should be made. Roentgen study of the larynx and neck by Dr. H. K. Pancoast's technic will give definite information as to the location and extent of the laryngeal lesion, and may also show evidence of metastasis or extension of the disease beyond the larynx. Repeated mirror observation of the progress of the lesion should be made, and if it does not clear up promptly, direct
Tucker G. A CASE OF CHRONIC HOARSENESS (ULCERATIVE LARYNGITIS) SHOWING TUBERCULOSIS AND CANCER IN THE SAME LESION. JAMA. 1931;96(19):1572–1573. doi:10.1001/jama.1931.27220450001007
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