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Article
December 15, 1934

BACTERIOPHAGE THERAPY: REVIEW OF THE PRINCIPLES AND RESULTS OF THE USE OF BACTERIOPHAGE IN THE TREATMENT OF INFECTIONS

Author Affiliations

NEW HAVEN, CONN.

JAMA. 1934;103(24):1847-1853. doi:10.1001/jama.1934.72750500003009
Abstract

Bacteriophage Treatment in Other Suppurative Conditions.—  The various accounts of the treatment of suppurative conditions with bacteriophage include cases in which the colon bacillus or staphylococcus, separately or together, were involved. In cases of mixed infections mixed bacteriophages, polyvalent for colon bacillus and staphylococcus, were used.There have been a number of reports of the successful use of bacteriophage in the treatment of infected wounds. McKinley74 reported good results in the treatment of three staphylococcic wound infections but noted marked reactions even when the bacteriophage was applied in the form of a wet dressing. Rice57 records excellent results in forty of forty-four wound infections, Dutton,56 good results in forty cases. In these cases the bacteriophage was instilled into the wound or applied in the form of a wet dressing. Boyce, Lampert and McFetridge65 treated forty-six wound cases with only two failures. Schultz53 reports that eight

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