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To the Editor:—
In the paper on arteriosclerosis and varicose veins by Drs. Lake, Pratt and Wright (The Journal, June 27, p. 696) appears the statement: "Although years of study by numerous workers have been devoted to this great enigma of biology, it can be fairly stated that today it is not known whether arteriosclerosis should be considered as a disease or as a purely degenerative process."The arterial lesions that are discussed in this paper are largely due to atherosclerosis, after primary spasmodic processes and the minor Mönckeberg's sclerosis are excluded. Atherosclerosis is not a "purely degenerative process." It is a complex disease as specific in character as the infectious diseases. Unlike so-called senile sclerosis, a negative condition due to passive dilatation of weakness of arterial walls, atherosclerosis is an active disease of positive quality, which may even be characterized as an aggressive disease when it kills robust boys
Leary T. ARTERIOSCLEROSIS AND VARICOSE VEINS. JAMA. 1942;119(13):1041. doi:10.1001/jama.1942.02830300053026
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