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February 2, 1935


JAMA. 1935;104(5):391-393. doi:10.1001/jama.1935.02760050037009

According to Barr,1 " 'calcinosis' is the term used to describe a deposit of calcium in or under the skin. It has also been applied to more or less scattered deposits in the subcutaneous tissues.... 'Calcinosis circumscripta' is a condition in which calcification is limited to the skin. It occurs almost always in the upper extremities, especially in the fingers, and interferes little with the general health of the patient.... Careful history... usually reveals that the patients have suffered from cold hands since early childhood and that the calcium deposits have occurred gradually."

This condition was apparently first reported about 1855, and since then there have been many cases reported, all stressing to some degree the relations of the blood serum calcium and phosphorus. By far the most exhaustive study of modern times is that of Barr, whose admirable definition has been given. He lists 172 references to the literature