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March 2, 1935


Author Affiliations

From the Department of Pharmacology and Experimental Therapeutics, Johns Hopkins University School of Medicine.

JAMA. 1935;104(9):738-741. doi:10.1001/jama.1935.92760090006012a

Note.  This article and the articles in the previous issues ofThe Journalare part of a series published under the auspices of the Council on Pharmacy and Chemistry. Other articles will appear in succeeding issues of The Journal. When completed, this series will be published in book form.—Ed.The primary structural elements of the posterior lobe of the hypophysis are the neuroglial cells, the pituicytes and the nerve fibers. The neuroglial cells resemble those found elsewhere in the central nervous system. In the pituitary some of them have become differentiated to form pituicytes,1 highly branched cells that have granules in the cytoplasm. The presence and significance of nerve fibers in the posterior lobe are still an open question.

ORIGIN AND PATH OF ESCAPE OF THE SECRETION  None of these structures, with the exception perhaps of the pituicytes, are regarded as secreting elements in the ordinary sense.