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Medical News & Perspectives
November 22/29, 2016

Pioneering Geneticist Explains Ambitious Plan to “Write” the Human Genome

JAMA. 2016;316(20):2074-2076. doi:10.1001/jama.2016.10673

A little over a quarter century ago, scientists officially launched the Human Genome Project at the National Institutes of Health, a plan to “read” the approximately 3 billion DNA base pairs that make up a human blueprint. Now, a group of researchers is proposing the next incarnation: an initiative to synthesize, or “write,” large portions of genomes. Weeks after a controversial closed meeting at Harvard in May, the group penned a perspective in Science publicly announcing plans to launch the Human Genome Project-write (HGP-write) this year with $100 million from public, private, philanthropic, industry, and academic funders.