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July 7, 1928


JAMA. 1928;91(1):30-31. doi:10.1001/jama.1928.02700010034012

Of the major problems of medicine, few have been more refractory to solution than the problem of arthritic and rheumatoid disability. From the time of Hippocrates this problem has been recognized as an entity; the ravages of arthritic disorders affected men in the stone age, and even reptiles of geological periods long antedating the advent of man. In spite of the fact that arthritis is the oldest disease entity of which there is historical record, investigative work as to its causes has been less intense and knowledge of its true nature has remained more meager than with many less widespread conditions. The explanation is to be found partly in the refractory nature of the disease itself but also in the fact that for some reason the rheumatoid problem has been thrown into the limbo of uninteresting and hence unprofitable chapters of medicine. As a result, hosts of sufferers drift into