Willan,1 in 1808, was the first to describe a case of purpura associated with violent vomiting, excruciating pains in the bowels, and anasarcous swellings of the legs, thighs and hands. Schönlein,2 in 1848, emphasized the arthritic and Henoch,3 in 1868, the visceral manifestations. Osler,4 in 1895, wrote of the constant association of various erythematous lesions of the skin with purpura and with abdominal pain and was criticized at the time for including such a varied group of cases under one head. It is generally agreed that his observations and his association were entirely correct. Furthermore, it is felt that the skin manifestations, especially erythema, urticaria, angioneurotic edema and purpura, the abdominal crises, the arthritic pains and the type of nephritis are manifestations of a single pathologic process. The present series includes thirteen children from the ages of 10 months to 12 years, observed at the Johns
TRIMBLE IR. ERYTHEMATOUS GROUP OF SKIN DISEASES WITH ESPECIAL REFERENCE TO ABDOMINAL PAIN. JAMA. 1931;96(24):2010–2014. doi:10.1001/jama.1931.02720500004002
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