The Health Organization of the League of Nations publishes1 the results of an inquiry into the treatment of syphilis carried out in five countries (Denmark, France, Germany, Great Britain and the United States) ; ninety-three clinics in these countries have contributed to this inquiry and 13,198 case records of primary and secondary syphilis have been analyzed.
Guided by the principles revealed by the study of these records, the experts who have collaborated2 have adopted the following recommendations, which are of great interest to syphilologists, public health officers and private practitioners:
1. Treatment should be recommended as early as possible in the seronegative primary stage. In this connection, the fullest possible use should be made, for purposes of diagnosis, of the microscopic examination of secretion from primary lesions or from lymph glands.
2. It should be emphasized that, prior to the institution of either of the systems of
LEAGUE OF NATIONS INVESTIGATION AND REPORT ON TREATMENT OF EARLY SYPHILIS. JAMA. 1935;104(15):1329–1330. doi:10.1001/jama.1935.92760150008010a
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