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August 4, 1928

Urinary Analysis and Diagnosis by Microscopical and Chemical Examination.

JAMA. 1928;91(5):346. doi:10.1001/jama.1928.02700050052035

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The laboratory part of this publication furnishes a complete survey of reliable methods for the examination of the urine. Two features are especially instructive. One is the minute description of the details of the investigatory procedures, and the other is the great number of illustrations demonstrating the various microscopic appearances. The clinical deductions and the discussions of pathology are susceptible of some exceptions. For instance, the statement that chronic nephritis may be diagnosed by the microscopic examination of the urine though only a moderate amount of albuminuria is present and no casts at all are found leaves outside of consideration the fact that in such instances the diagnosis is based on the recognition of functional disturbances such as the retention of organic metabolic end-products, rise of blood pressure and changes in the ocular background. The assertion that every renal inflammation is primarily an interstitial one and that interstitial nephritis is

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