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May 4, 1935


Author Affiliations

Dallas, Texas

JAMA. 1935;104(18):1594-1595. doi:10.1001/jama.1935.92760180001008

My purpose in this report is to present a case of Staphylococcus aureus meningitis in which a complete recovery was made during treatment with Staphylococcus aureus bacteriophage administered intraspinally. Conclusions should not be drawn from one case. A single successfully treated case, however, seems worthy of being added to the scant literature relative to this almost invariably fatal illness, as a series of treated staphylococcic meningitis cases is difficult to obtain. Schless1 reported the first and only case in detail in the literature of a successfully treated Staphylococcus aureus meningitis with bacteriophage administered intraspinally. He used larger amounts of the bacteriophage than were used in the present case, but his results were very similar. Stout2 reported treating successfully two cases of staphylococcic meningitis with bacteriophage, but no details of the case were given.

In this paper no attempt will be made to discuss bacteriophage theraphy itself, as this