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Antibiotic therapy is the cornerstone of management for patients hospitalized with community-acquired pneumonia (CAP), yet the optimal duration of therapy remains unknown. Whereas personalized medicine has gained traction in the treatment of many diseases, adults hospitalized with CAP have traditionally been treated with relatively standard, prolonged antibiotic courses lasting 7 to 14 days. Personalizing the most appropriate treatment duration should balance the risks of illness progression or complications associated with abbreviated treatment durations and those of antibiotic resistance and adverse drug events associated with prolonged antibiotic treatment.
Lee JS, Giesler DL, Fine MJ. Duration of Antibiotic Therapy for Community-Acquired Pneumonia in the Era of Personalized Medicine. JAMA. 2016;316(23):2544–2545. doi:10.1001/jama.2016.17589
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