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June 27, 1931


Author Affiliations

Rochester, Minn.
From the Division of Medicine, the Mayo Clinic.

JAMA. 1931;96(26):2194-2196. doi:10.1001/jama.1931.27220520001008

Thrombosis may occur in any part of the vascular system but is most frequently encountered in the pelvic veins and in the veins of the lower extremities. It occurs during the course of the puerperium and in the convalescent period following abdominal operations. There is usually a systemic elevation of temperature of from 1 to 3 degrees fahrenheit associated with local pain and tenderness along the course of the vein involved, followed by swelling and cyanosis of the extremity involved. Thrombosis is much less common in the upper extremities, and primary thrombosis of the axillary vein is relatively rare. Cadenat,1 in 1920, and Löhr,2 in 1929, both give Schrötter credit for first describing this clinical syndrome in 1884. Cadenat reviewed twenty-four cases from the literature. The right arm was involved in twenty-one cases and the left arm in three. More than fifty cases have been reported. Gould and