Observations on the renal circulation were carried out as early as 1883, when Cohnheim and Roy1 applied the oncometer to this problem. Since then Landergren and Tigerstedt,1 using the Ludwig stromuhr, and others,2 using modifications of the stromuhr method, have extended the observations on direct measurements of renal blood flow. Van Slyke and his co-workers3 contributed an indirect method based on the renal urea extraction ratio and arrived at the conclusion that the urea clearance varied directly as the blood flow. These methods are not applicable to a study of renal blood flow in man. Smith and his associates4 developed the diodrast method, an indirect one, applicable to human subjects. Using this method, White5 and others6 have contributed additional studies.
Barbour7 and Lazinski8 studied circulatory adjustments to hot environmental temperatures, but their work did not include the effect of such temperatures
BYFIELD GV, TELSER SE, KEETON RW. RENAL BLOOD FLOW AND GLOMERULAR FILTRATION: AS INFLUENCED BY ENVIRONMENTAL TEMPERATURE CHANGES. JAMA. 1943;121(2):118–123. doi:10.1001/jama.1943.02840020026006
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: