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June 1, 1935


Author Affiliations

From the Departments of Dermatology and Physiology, University of Illinois College of Medicine.

JAMA. 1935;104(22):1976-1979. doi:10.1001/jama.1935.02760220022007

For a long time it has been suspected that yeast infections of the skin are associated with some error in carbohydrate metabolism. The condition is most prevalent among Jews, a people who are prone to difficulties in sugar metabolism. Moreover, yeasts require a ready supply of sugar to thrive. In addition, yeast infections are fairly common in diabetic patients and in the genital tract of diabetic women. In spite of this evidence, no carbohydrate metabolic error has been definitely linked with the majority of cases of moniliasis. Examination of the blood of most of the affected subjects has not shown it to have any deviations from the normal. Since it would indeed be surprising if any carbohydrate metabolic change should be present without showing itself in the blood, and none has been regularly found there, investigators have been discouraged from looking elsewhere.

There are several reasons, however, for suspecting that