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Comment & Response
February 7, 2017

Association of Maternal Diabetes With Autism in Offspring

Author Affiliations
  • 1Department of Research and Evaluation, Southern California Permanente Medical Group, Pasadena

Copyright 2017 American Medical Association. All Rights Reserved.

JAMA. 2017;317(5):537-538. doi:10.1001/jama.2016.20122

To the Editor On behalf of the coauthors of the study “Association of Maternal Diabetes With Autism in Offspring” by Xiang et al,1 I write to explain errors that recently came to our attention.

We are currently conducting additional analyses on the primary data set used in the study. In the course of those analyses, we discovered that maternal preexisting diabetes by International Classification of Diseases, Ninth Revision codes had accidentally been included as one condition in defining maternal history of comorbidity. This maternal history of comorbidity was a covariate that was included in the adjusted analyses to assess the relationship between maternal gestational diabetes mellitus and preexisting maternal diabetes and the risk of autism spectrum disorders (ASD) in offspring.