[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.238.190.122. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
March 6, 1943

LIVER FUNCTION TESTS: GENERAL EVALUATION OF LIVER FUNCTION TESTS, AND AN APPRAISAL OF THE COMPARATIVE SENSITIVITY AND RELIABILITY OF THE NEWER TESTS, WITH PARTICULAR EMPHASIS ON THE CEPHALINCHOLESTEROL FLOCCULATION TEST, THE INTRAVENOUS HIPPURIC ACID TEST AND AN IMPROVED BROMSULPHALEIN TEST WITH A NEW NORMAL STANDARD

Author Affiliations

From the Gastro-Intestinal Division of the Medical Department, Henry Ford Hospital.

JAMA. 1943;121(10):723-728. doi:10.1001/jama.1943.02840100009003
Abstract

This discussion deals, first, with a general evaluation of liver function tests and with the importance of adequate and carefully conducted normal control studies. In the second place, the comparative sensitivity and reliability of the newer tests, in relation to each other and to the older tests, as evaluated in a recent publication of ours,1 are reviewed and summarized. Finally, an improved bromsulphalein method has been developed, using 5 mg. of the dye per kilogram and employing a new time interval as the normal standard for complete disappearance of the dye from the blood stream.

GENERAL EVALUATION OF LIVER FUNCTION TESTS  Liver function tests offer valuable aid in the evaluation of hepatic cell function. However, these tests should be regarded only as an aid to clinical and other laboratory findings in the diagnosis of the exact pathologic conditions. Liver function tests indicate the existing functional state of

×